Research Paper Volume 13, Issue 18 pp 22474—22489

Identification of genes and pathways leading to metastasis and poor prognosis in melanoma

Inactivation of CDK4 or VWF inhibits the invasion and migration of melanoma. (A, B) Closure percentage of the si-CDK4 or si-VWF group was significantly lower than that of the Control and si-Control groups. (C, D) Relative count of invading cells of the si-CDK4 or si-VWF group was significantly lower than that of the Control and si-Control groups. Asterisks indicate statistically significant difference (**: p

Figure 7. Inactivation of CDK4 or VWF inhibits the invasion and migration of melanoma. (A, B) Closure percentage of the si-CDK4 or si-VWF group was significantly lower than that of the Control and si-Control groups. (C, D) Relative count of invading cells of the si-CDK4 or si-VWF group was significantly lower than that of the Control and si-Control groups. Asterisks indicate statistically significant difference (**: p<0.01, one-way ANOVA).