Research Paper Volume 13, Issue 18 pp 22474—22489

Identification of genes and pathways leading to metastasis and poor prognosis in melanoma

Correlation between BRAFV600E expression and expression of key genes. (A) The expression of CDK2, CDK4, KIT, and VWF is significantly correlated with that of BRAFV600E. The numbers in the upper right corner represent the p value, and the numbers in the lower left corner represent the correlation coefficient. (B–F) Expression trend of CDK2, CDK4, KIT, and VWF after inhibiting the expression of BRAFV600E.

Figure 8. Correlation between BRAFV600E expression and expression of key genes. (A) The expression of CDK2, CDK4, KIT, and VWF is significantly correlated with that of BRAFV600E. The numbers in the upper right corner represent the p value, and the numbers in the lower left corner represent the correlation coefficient. (BF) Expression trend of CDK2, CDK4, KIT, and VWF after inhibiting the expression of BRAFV600E.