Research Paper Volume 13, Issue 18 pp 21991—22029

Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression

Chord-dendrogram of the interactions between differently expressed miRNAs and altered genes in CRC. The interactions between the 25 differently expressed miRNAs identified and the 173 experimentally validated target genes were obtained through MirTarBase. Target genes’ role in CRC is according to CoReCG database. All targets are represented in grey, while each miRNA is represented by one colour. MiRNA:target interactions are represented by a line of the same colour of the respective miRNA. The size of rectangle next to the name of the miRNAs and target genes is proportional to the number of interactions they perform.

Figure 4. Chord-dendrogram of the interactions between differently expressed miRNAs and altered genes in CRC. The interactions between the 25 differently expressed miRNAs identified and the 173 experimentally validated target genes were obtained through MirTarBase. Target genes’ role in CRC is according to CoReCG database. All targets are represented in grey, while each miRNA is represented by one colour. MiRNA:target interactions are represented by a line of the same colour of the respective miRNA. The size of rectangle next to the name of the miRNAs and target genes is proportional to the number of interactions they perform.