Research Paper Volume 13, Issue 18 pp 21991—22029

Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression

Individual miRNA overall survival (OS) prognosis for stage III and stage IV patients. (A) Stage III OS Kaplan-Meier curve for miR-133b (p-value = 0.047, Log rank; HR = 2.28) (B) Stage IV OS Kaplan-Meier curve for miR-129-5p (p-value = 0.021, Log rank; HR = 4.23). Time is represented in years. Higher (in red) and Lower (in blue) expression groups represent the patients with miRNA expression above and below miRNAs’ median expression, respectively. Censored data is represented by small plus signs in each group. The number of patients at risk for each group and per time point is shown in the table below each graph. HR, hazard ratio.

Figure 8. Individual miRNA overall survival (OS) prognosis for stage III and stage IV patients. (A) Stage III OS Kaplan-Meier curve for miR-133b (p-value = 0.047, Log rank; HR = 2.28) (B) Stage IV OS Kaplan-Meier curve for miR-129-5p (p-value = 0.021, Log rank; HR = 4.23). Time is represented in years. Higher (in red) and Lower (in blue) expression groups represent the patients with miRNA expression above and below miRNAs’ median expression, respectively. Censored data is represented by small plus signs in each group. The number of patients at risk for each group and per time point is shown in the table below each graph. HR, hazard ratio.