Research Paper Volume 13, Issue 18 pp 22516—22527

miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis

MiR-320 OE heightened the TGF-β, IL-6, t-STAT3, and p-STAT3 signaling and suppressed PTEN. (A) Representative Western blots in the left ventricular tissues; (B) The quantitative analysis of TGF-β, IL-6, p-STAT3, t-STAT3 and PTEN; P

Figure 5. MiR-320 OE heightened the TGF-β, IL-6, t-STAT3, and p-STAT3 signaling and suppressed PTEN. (A) Representative Western blots in the left ventricular tissues; (B) The quantitative analysis of TGF-β, IL-6, p-STAT3, t-STAT3 and PTEN; P < 0.05; miR-320 OE vs. model.