Research Paper Volume 13, Issue 18 pp 22516—22527

miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis

PTEN was involved in miR-320 mimics-induced cardiac fibrosis. (A) Representative Western blots in fibroblasts with or without orexin B injection; (B) The quantitative analysis of TGF-β, IL-6, p-STAT3, and PTEN with or without orexin B injection; P C) The proliferation of fibroblasts treated with miR-320 mimics, inhibitor or negative control (NC) was measured by CCK8 assay.

Figure 6. PTEN was involved in miR-320 mimics-induced cardiac fibrosis. (A) Representative Western blots in fibroblasts with or without orexin B injection; (B) The quantitative analysis of TGF-β, IL-6, p-STAT3, and PTEN with or without orexin B injection; P < 0.05. (C) The proliferation of fibroblasts treated with miR-320 mimics, inhibitor or negative control (NC) was measured by CCK8 assay.