Research Paper Volume 13, Issue 18 pp 22528—22543

Inhibition of FSTL3 abates the proliferation and metastasis of renal cell carcinoma via the GSK-3β/β-catenin signaling pathway

FSTL3 influenced RCC growth. ACHN cells transiently transfected along with the overexpression plasmids of FSTL3 were transfused under the skin of the experimental mice. (A–C) We observed and measured the tumor growth in mice and drew the growth curve and weighted histogram; (D) Western Blot evaluated the protein profiles of E-cadherin, Twist, and Slug. (E) IHC determined E-cadherin expression in the tumor tissues. *PPP

Figure 5. FSTL3 influenced RCC growth. ACHN cells transiently transfected along with the overexpression plasmids of FSTL3 were transfused under the skin of the experimental mice. (AC) We observed and measured the tumor growth in mice and drew the growth curve and weighted histogram; (D) Western Blot evaluated the protein profiles of E-cadherin, Twist, and Slug. (E) IHC determined E-cadherin expression in the tumor tissues. *P<0.05, **P<0.01, ***P<0.001 (vs. the NC group). N=5.