Research Paper Volume 13, Issue 21 pp 24050—24070

Identification of KIF4A as a prognostic biomarker for esophageal squamous cell carcinoma

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Figure 2. PPI network construction and Hub gene selection. The PPI network of DEGs was constructed using Cytoscape (A). The Venn diagram of the overlapped 6 hub genes from the topological algorithms in the cytoHubba module (B). The heatmap of 6 hub genes (C). The expression difference of the 6 hub genes between tumor tissues and normal tissues by paired test from GEO (D).