Figure 3. The survival analyses for hub genes. CDKN3 and KIF4A were identified to have an adverse effect on the prognosis of overall survival for patients with ESCC by UALCAN (A) and GEPIA2 (B) analysis. Gene expression of 6 hub genes between invading and non-invading cells based on the GSE21293 (C). Association between clinical staging, nodal metastasis status of ESCC and expression levels of the KIF4A by UALCAN analysis (D).