Research Paper Volume 13, Issue 18 pp 22092—22108

Adulthood systemic inflammation accelerates the trajectory of age-related cognitive decline


Figure 2. Vehicle and LPS treated animals learn the spatial discrimination and differences in memory emerge at 18 months, 12 months after treatment. Symbols represent mean escape path length (± SEM) for vehicle (open circles) and LPS treated (filled circles) animals over the training blocks for (A) spatial discrimination. (B) Box and whisker plots and individual DI scores from the acquisition, 2 hr and 24 hr probe trials. Pound sign indicates significant difference from chance (p < 0.05). Asterisk indicates significant treatment difference (p < 0.05).