Figure 4 — LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway

Research Paper|Volume 13, Issue 21|pp. 24071–24085

LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway

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Figure 4.The effects of miR-214 overexpression on RA-FLS-mediated inflammation. (A–D) The effects of miR-214 overexpression on proliferation, metastasis, and production of inflammatory molecules and MMPs in RA-FLS (n=3). (E–I) The effects of miR-214 overexpressing RA-FLS on primary macrophages and chondrocytes (n=3). Data represent the mean ± SEM; *p < 0.05, Student’s t-test.