Research Paper Volume 13, Issue 21 pp 24101—24116

Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation


Figure 10.

A schema diagram displaying the inhibitory effects of curcumol on glioma tumorigenesis and TMZ-resistance. Based on the findings of the present, FOXD2-As1 might be a molecular target of curcumol treatment, and that curcumol performs its functions in glioma cells by repressing FOXD2-As1-induced EZH2 activity.