COVID-19 Research Paper Volume 13, Issue 21 pp 23895—23912

Role of tumor necrosis factor-α in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia

Variation in radiological findings in patients with severe and critical COVID-19 during disease course. Chest computed tomography (CT) shows severe multiple patchy shadows in both lungs on day 20 of symptom onset (examined upon admission) before treatment (A). Chest CT shows improved patchy shadows on day 39 of symptom onset for the same patient after treatment (B). Chest CT for a 68-year-old female who presented with high fever and dyspnea before treatment (C). Followed-up CT assessment was not performed because the patient died of her severe illness.

Figure 1. Variation in radiological findings in patients with severe and critical COVID-19 during disease course. Chest computed tomography (CT) shows severe multiple patchy shadows in both lungs on day 20 of symptom onset (examined upon admission) before treatment (A). Chest CT shows improved patchy shadows on day 39 of symptom onset for the same patient after treatment (B). Chest CT for a 68-year-old female who presented with high fever and dyspnea before treatment (C). Followed-up CT assessment was not performed because the patient died of her severe illness.