Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 21 pp 24339—24348
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway
Figure 1. High expression of miR-15a indicated a poor prognosis of glioma. (A) Microarray analysis used to identify the differential expressed miRNAs in 3 paired glioma tissues. (B) The mRNA expression of miR-15a in adjacent normal tissues and cancer tissues of glioma was detected by qRT-PCR. (C) MiR-15a level in normal astrocytes and glioma cell lines (U87 and SHG139) was measured. (D) The overall survival rate of glioma patients with high or low expression of miR-15a. Data were expressed as mean ± SD.*P < 0.05.