Research Paper Volume 13, Issue 21 pp 24417—24431

RIP3 Inhibition ameliorates chronic constriction injury-induced neuropathic pain by suppressing JNK signaling

The variation in the expression of RIP3, p-JNK, and c-Fos in RIP3-overexpressed astrocytes after treatment with RIP3 inhibitors and JNK inhibitors. (A) The levels of RIP3, p-JNK, JNK, c-Fos and GAPDH in diverse groups of astrocytes. (B) The ratio of RIP3 or c-Fos to GAPDH and the ratio p-JNK to JNK were quantified with Image J. Data are shown as mean SD (n = 8). *P #P

Figure 5. The variation in the expression of RIP3, p-JNK, and c-Fos in RIP3-overexpressed astrocytes after treatment with RIP3 inhibitors and JNK inhibitors. (A) The levels of RIP3, p-JNK, JNK, c-Fos and GAPDH in diverse groups of astrocytes. (B) The ratio of RIP3 or c-Fos to GAPDH and the ratio p-JNK to JNK were quantified with Image J. Data are shown as mean SD (n = 8). *P < 0.05, in contrast with the M1830 cells within groups, #P < 0.05, in contrast with the control group.