Research Paper Volume 13, Issue 21 pp 24464—24475

Propofol suppresses the growth and invasion of cervical carcinoma cells by inhibiting MIR155HG

Propofol suppresses SiHa cell growth in vivo. (A) Photographs of representative tumor tissue in tumor xenografts five weeks after propofol treatment. (B) Quantitative analysis of tumor volume. (C) Quantitative analysis of tumor weight. (D) Body weight. (E) MIR155HG expressions in tumor tissue were determined by qRT-PCR. (F) The expression of E-cadherin and N-cadherin were determined using immunohistochemical staining. (G) Western blot analysis for E-cadherin and N-cadherin in tumor tissue. (H) Representative images of the histologic lung metastases were analyzed using H&E staining. (I) The number of lung metastatic tumors were graphed. **P

Figure 5. Propofol suppresses SiHa cell growth in vivo. (A) Photographs of representative tumor tissue in tumor xenografts five weeks after propofol treatment. (B) Quantitative analysis of tumor volume. (C) Quantitative analysis of tumor weight. (D) Body weight. (E) MIR155HG expressions in tumor tissue were determined by qRT-PCR. (F) The expression of E-cadherin and N-cadherin were determined using immunohistochemical staining. (G) Western blot analysis for E-cadherin and N-cadherin in tumor tissue. (H) Representative images of the histologic lung metastases were analyzed using H&E staining. (I) The number of lung metastatic tumors were graphed. **P<0.01 compared with vehicle.