Research Paper Volume 13, Issue 22 pp 24621—24639

Construction of a genome instability-derived lncRNA-based risk scoring system for the prognosis of hepatocellular carcinoma

Unfavorable impact of AC145343.1 on HCC in vitro. (A) Kaplan–Meier curve of expression level of AC145343.1 on HCC patients using ENCORI. (B) Cell viability of HepG2 was significantly inhibited after AC145343.1 silencing. (C) Colony formation number was significantly decreased after AC145343.1 silencing compared to the control group. (D) Invasive ability of HepG2 was suppressed after AC145343.1 silencing manifested by transwell experiment. (E) Wound healing array demonstrated that AC145343.1-downregulated HepG2 cell exhibited obviously delay in wound healing when compared with the control group. *P**P***P

Figure 7. Unfavorable impact of AC145343.1 on HCC in vitro. (A) Kaplan–Meier curve of expression level of AC145343.1 on HCC patients using ENCORI. (B) Cell viability of HepG2 was significantly inhibited after AC145343.1 silencing. (C) Colony formation number was significantly decreased after AC145343.1 silencing compared to the control group. (D) Invasive ability of HepG2 was suppressed after AC145343.1 silencing manifested by transwell experiment. (E) Wound healing array demonstrated that AC145343.1-downregulated HepG2 cell exhibited obviously delay in wound healing when compared with the control group. *P<0.05, **P<0.01, ***P<0. 01.