Research Paper Volume 13, Issue 22 pp 24621—24639

Construction of a genome instability-derived lncRNA-based risk scoring system for the prognosis of hepatocellular carcinoma

Computational overview of genomic instability-related lncRNAs. Somatic mutations of each HCC sample were counted. Samples were divided into two groups, GU group (patients’ mutator phenotype ranked in the top 25%) and GS group (patients’ mutator phenotype ranked in the last 25%). Genomic instability-related lncRNAs were examined according to the difference of lncRNA expression profile between GU group and GS group.

Figure 8. Computational overview of genomic instability-related lncRNAs. Somatic mutations of each HCC sample were counted. Samples were divided into two groups, GU group (patients’ mutator phenotype ranked in the top 25%) and GS group (patients’ mutator phenotype ranked in the last 25%). Genomic instability-related lncRNAs were examined according to the difference of lncRNA expression profile between GU group and GS group.