Figure 4.The possible mechanism or interactive pathway from relevant information on ABO and plasma lipids phenotype. Mechanism of action for ABO variants may result in the vWF/ADAMTS13 and sE-selectin/ICAM1 functional change. Lastly, two pathways involving vWF/ADAMTS13 and the inflammatory markers (sE-selectin/ICAM1) that co-regulated lipid levels by O-linked glycosylation and effects on each other were speculated.
