Research Paper Volume 13, Issue 22 pp 24686—24709

Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma


Figure 1. Genomic mutation features in EC, EnOC, and En. (A) Hematoxylin-Eosin staining of EC and EnOC and En samples. (B) Mutant genes of EC and EnOC and En. (C) Point mutation frequency of five common mutant genes (PTEN, KRAS, CTNNB1, PI3K3CA, and ARID1A) in EC, EnOC, and En, the left column was the observed point mutation frequency, and the right was the expected point mutation frequency. (D) Top 20 mutation genes in EC, which were rank ordered following the number of mutated samples. (E) Top 20 mutation genes in EnOC. (F) The mutation percentage of the 17791 genes in various organs.