Research Paper Volume 13, Issue 22 pp 24686—24709

Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma


Figure 2. Gene enrichment analysis of 275 common mutation genes and their association with prognosis in EC. (A) Mutant genes of EC and EnOC. (B) Protein-protein interaction (PPI) network and enriched terms of the 275 overlapped mutant genes of EC and EnOC. (C) Pathway enrichment analysis of the 275 genes in EC. The genes marked in red belonged to the above-mentioned 275 genes, and the percentages indicated the proportion of mutations in this gene in EC. (D, E) Overall survival and disease-free survival analysis of the altered and unaltered group. Patients with these 275 gene mutations were classified as the altered group, and those without were classified as the unaltered group.