Research Paper Volume 13, Issue 22 pp 24686—24709
Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma
Figure 5. BRCA-associated features identified two signatures with different immune-associated expression patterns in EC. (A) The expression of CD4, CD8A, CD8B, CD3D, CD3E, CD3G, CD138, CD163, CSF1R, CD11B, CD2, CD161, CD1C, CCR7, CD123 of EC patients clustered by Signature 1. (B) The expression of CD4, CD8A, CD8B, CD3D, CD3E, CD3G, CD138, CD163, CSF1R, CD11B, CD2, CD161, CD1C, CCR7, CD123 of EC patients clustered by Signature 2. (C) The expression of BTLA, CD47, HAVCR2, KIR3DL3, KIR3DL2, LAG3, PDCD1, TDO2, TIGIT of EC patients clustered by Signature 1. (D) The expression of BTLA, CD47, HAVCR2, KIR3DL3, KIR3DL2, LAG3, PDCD1, TDO2, TIGIT of EC patients clustered by Signature 2. (E) The expression of CD226, CD27, CD40LG, CD96, CEACAM1, TNFRSF18, TNFSF14 of EC patients clustered by Signature 1. (F) The expression of CD226, CD27, CD40LG, CD96, CEACAM1, TNFRSF18, TNFSF14 of EC patients clustered by Signature 2. * P<0.05; ** P<0.01; ***P<0.001; ****P<0.0001; ns indicated that there was no significant statistical difference.