Research Paper Volume 13, Issue 22 pp 24686—24709

Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma


Figure 6. Evaluation of the effectiveness of olaparib in EC and EnOC in vitro. (A) Cell viability curve. (B) The IC50 value of cell lines to Olaparib. (C, D) Cell migration evaluated with Transwell assay in A2780 and KLE. (E, F) Apoptosis assay with flow cytometry and the statistical chart. (G) Apoptosis analysis with TUNEL assay. (H, I) Cell cycle analysis and the statistical chart. * P<0.05; ** P<0.01; ***P<0.001; ****P<0.0001; ns indicated that there was no significant statistical difference.