Research Paper Volume 13, Issue 22 pp 24850—24865

Long noncoding RNA NEAT1 inhibits the acetylation of PTEN through the miR-524-5p /HDAC1 axis to promote the proliferation and invasion of laryngeal cancer cells


Figure 9. Silence of NEAT1 suppressed tumor growth in vivo. (A) Tumor growth curves in two groups. (B) Representative images of TU212 cells from nude mice. (C) The effect of NEAT1 silence on tumor weight. The expression of NEAT1 (D), miR-524-5p (E), PTEN, Ac-PTEN, AKT, p-AKT and HDAC1 (F) in tumor tissues was detected with Western blotting. * P < 0.05, ** P < 0.01 versus shRNA.