Progressive reorganization of mitochondrial apparatus in aging skeletal muscle of naked mole rats (<i>Heterocephalus glaber)</i> as revealed by electron microscopy: potential role in continual maintenance of muscle activity

Valeriya Vays; Irina Vangely; Chupalav Eldarov; Susanne Holtze; Thomas Hildebrandt; Lora Bakeeva; Vladimir Skulachev

doi:doi:10.18632/aging.203720

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Research Paper Volume 13, Issue 22 pp 24524—24541

Progressive reorganization of mitochondrial apparatus in aging skeletal muscle of naked mole rats (Heterocephalus glaber) as revealed by electron microscopy: potential role in continual maintenance of muscle activity

Figure 5. Ultrastructure of mitochondria in skeletal muscle of 7-year-old naked mole rat. (A) Cross section of muscle fiber. Clusters of large mitochondria in the subsarcolemmal area are indicated by arrows 1. Mitochondrion of specific ultrastructure, which is demonstrated in Figure 5B, is indicated by arrow 2. (B) Mitochondrion which specific ultrastructure, cristae in form of curled, wave-like structures are indicated by arrows. (C) Longitudinal section of muscle fiber, large clusters of mitochondria localized along myofibrils are indicated by arrows.