Research Paper Volume 13, Issue 22 pp 24542—24559

Increased proliferation and differentiation capacity of placenta-derived mesenchymal stem cells from women of median maternal age correlates with telomere shortening


Figure 6. Maternal age influences PDMSCs telomere length and correlates with MSCs characteristics. (A) Graph showing the telomere length for all 5 age groups (B) Schematic representation of hypothesis for reduced telomere shortening. (C) Graph Showing correlation between age factor and cellular self-renewal capacity, cellular multipotency capacity and cellular differentiation capacity. Group A: 18-21; Group B: 22-25; Group C: 26-30; Group D: 31-35; Group E: 36 and over. *, p<0.05; **, p<0.01; ***, p<0.0005; ****, p<0.0001.