Research Paper Volume 13, Issue 22 pp 24542—24559

Increased proliferation and differentiation capacity of placenta-derived mesenchymal stem cells from women of median maternal age correlates with telomere shortening


Figure 7. Graphical summary of the impact of maternal age in PDMSCs cellular properties. Group A: 18-21 and Group E: 36 and over showed reduced self-renewal and proliferative capacities with reduced lineage differentiation ability. In contrast both groups showed longer telomere length. Group B: 22-25, Group C: 26-30 and Group D: 31-35 demonstrated higher self-renewal and proliferative capacity with higher lineage differentiation ability with reduced telomere length.