Research Paper Volume 13, Issue 23 pp 25138—25152

LncRNA SNHG3 promotes gastric cancer cell proliferation and metastasis by regulating the miR-139-5p/MYB axis


Figure 1. Gastric cancer cells and tissues exhibit SNHG3 upregulation that is correlated with poor patient prognosis. (A) SNHG3 expression was assessed in gastric cancer tissues in the TCGA database, *P<0.01. (B) SNHG3 expression was assessed in 26 paired gastric cancer tumor and paracancerous tissues via qPCR, *P<0.01. (C) SNHG3 expression was assessed via qPCR in gastric cancer cells (BGC-823, AGS, MGC-803, and HGC-27) and control GES-1 cells. *P<0.01 vs. GES-1 cells. (D) Gastric cancer patient survival for individuals in the TCGA database was assessed via the Kaplan-Meier method (log-rank, P=0.0007).