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The cover features Figure 5 "Immunofluorescent detection of γ-H2AX in murine hair follicles" from Kudlova et al.

Volume 13, Issue 23

15 December, 2021
pp 24917—25603

About the Cover

The cover features Figure 5 "Immunofluorescent detection of γ-H2AX in murine hair follicles" from Kudlova et al.


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Editorials

Immunometabolism as predictor of frailty

Johanna M. Gostner, Blanca Laffon, Thomas K. Felder,
https://doi.org/10.18632/aging.203737 pp 24917—24918
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Late-life fasting imparts resiliency and protein persulfidation

Jie Yang, Betemariam Sharew, Christopher Hine,
https://doi.org/10.18632/aging.203758 pp 24919—24921
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Raman microspectroscopy: sub-cellular chemical imaging of aging

Lisa Liendl, Markus Schosserer,
https://doi.org/10.18632/aging.203785 pp 24922—24923
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Meeting Report

The 2021 FASEB science research conference on NAD metabolism and signaling

Vera Gorbunova, Marcus Buschbeck, Xiaolu A. Cambronne, Karthikeyani Chellappa, Daniela Corda, Juan Du, Marc Freichel, Jonathan Gigas, Alexander E. Green, Feng Gu, Iva Guberovic, Aravinthkumar Jayabalan, Imrankhan Khansahib, Sarmistha Mukherjee, Andrei Seluanov, Matthew A. Simon, Lars J. Sverkeli, Nora Kory, Daniel C. Levine, Ivan Matic, Andrey Nikiforov, Johannes G.M. Rack, Shin-Ichiro Imai, David A. Sinclair, Debra Toiber, Yongjuan Zhao, Raul Mostoslavsky, Lee Kraus, Andreas H. Guse,
https://doi.org/10.18632/aging.203766 pp 24924—24930
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Research Papers

COVID-19
Multicenter study evaluating one multiplex RT-PCR assay to detect SARS-CoV-2, influenza A/B, and respiratory syncytia virus using the LabTurbo AIO open platform: epidemiological features, automated sample-to-result, and high-throughput testing

Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Jung-Chung Lin, Kuo-Ming Yeh, Ya-Sung Yang, Chien-Wen Chen, Shan-Shan Hsieh, Sheng-Hui Tang, Cherng-Lih Perng, Feng-Yee Chang, Kuo-Sheng Hung, En-Sung Chen, Mei-Hsiu Yang, Hung-Sheng Shang,
https://doi.org/10.18632/aging.203761 pp 24931—24942
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COVID-19
Impact of chemotherapy and immunotherapy on the composition and function of immune cells in COVID-19 convalescent with gynecological tumors

Tianyu Qin, Ensong Guo, Funian Lu, Yu Fu, Si Liu, Rourou Xiao, Xue Wu, Chen Liu, Chao He, Zizhuo Wang, Xu Qin, Dianxing Hu, Lixin You, Fuxia Li, Xi Li, Xiaoyuan Huang, Ding Ma, Xiaoyan Xu, Bin Yang, Junpeng Fan,
https://doi.org/10.18632/aging.203739 pp 24943—24962
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Metabolomic profiling of plasma from middle-aged and advanced-age male mice reveals the metabolic abnormalities of carnitine biosynthesis in metallothionein gene knockout mice

Yoshito Kadota, Asuka Yano, Takashige Kawakami, Masao Sato, Shinya Suzuki,
https://doi.org/10.18632/aging.203731 pp 24963—24988
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Longitudinal trajectories and determinants of human fungiform papillae density

Ajoy C. Karikkineth, Eric Y. Tang, Pei-lun Kuo, Luigi Ferrucci, Josephine M. Egan, Chee W. Chia,
https://doi.org/10.18632/aging.203741 pp 24989—25003
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An efficient, non-invasive approach for in-vivo sampling of hair follicles: design and applications in monitoring DNA damage and aging

Natalie Kudlova, Hanus Slavik, Pavlina Duskova, Tomas Furst, Josef Srovnal, Jiri Bartek, Martin Mistrik, Marian Hajduch,
https://doi.org/10.18632/aging.203744 pp 25004—25024
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Serum levels of proinflammatory cytokines and selected bioelements in perimenopausal women with regard to body mass index

Anna Maria Cybulska, Kamila Rachubińska, Małgorzata Szkup, Daria Schneider-Matyka, Irena Baranowska-Bosiacka, Dariusz Chlubek, Anna Lubkowska, Mariusz Panczyk, Joanna Sołek-Pastuszka, Elżbieta Grochans,
https://doi.org/10.18632/aging.203754 pp 25025—25037
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Physical and functional measures predicting long-term mortality in community-dwelling older adults: a comparative evaluation in the Singapore Longitudinal Ageing Study

Chin Yee Cheong, Philip Yap, Xinyi Gwee, Denise Q.L. Chua, Shiou Liang Wee, Keng Bee Yap, Tze Pin Ng,
https://doi.org/10.18632/aging.203756 pp 25038—25054
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IGFBP-6/sonic hedgehog/TLR4 signalling axis drives bone marrow fibrotic transformation in primary myelofibrosis

Lucia Longhitano, Daniele Tibullo, Nunzio Vicario, Cesarina Giallongo, Enrico La Spina, Alessandra Romano, Sofia Lombardo, Marina Moretti, Francesco Masia, Anna Rita Daniela Coda, Santina Venuto, Paolo Fontana, Rosalba Parenti, Giovanni Li Volti, Michelino Di Rosa, Giuseppe A. Palumbo, Arcangelo Liso,
https://doi.org/10.18632/aging.203779 pp 25055—25071
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Construction and validation of a metabolic gene-associated prognostic model for cervical carcinoma and the role on tumor microenvironment and immunity

Jinzhi Huang, Fei Luo, Mingjie Shi, Jiaxin Luo, Choudi Ma, Shangzheng Li, Yue Wei, Runmin Guo, Ting Li,
https://doi.org/10.18632/aging.203723 pp 25072—25088
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The isoflavone puerarin exerts anti-tumor activity in pancreatic ductal adenocarcinoma by suppressing mTOR-mediated glucose metabolism

Hengyue Zhu, Yanyi Xiao, Hangcheng Guo, Yangyang Guo, Youze Huang, Yunfeng Shan, Yongheng Bai, Xiangyang Lin, Hong Lu,
https://doi.org/10.18632/aging.203725 pp 25089—25105
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Landscape of the oncogenic role of fatty acid synthase in human tumors

Xulei Huo, Lairong Song, Da Li, Ke Wang, Yali Wang, Feng Chen, Liwei Zhang, Liang Wang, Junting Zhang, Zhen Wu,
https://doi.org/10.18632/aging.203730 pp 25106—25137
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LncRNA SNHG3 promotes gastric cancer cell proliferation and metastasis by regulating the miR-139-5p/MYB axis

Yan Xie, Li Rong, Min He, Yuyou Jiang, Haiyu Li, Li Mai, Fangzhou Song,
https://doi.org/10.18632/aging.203732 pp 25138—25152
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A circadian rhythm-related gene signature associated with tumor immunity, cisplatin efficacy, and prognosis in bladder cancer

Ranran Zhou, Xinyu Chen, Jingjing Liang, Qi Chen, Hu Tian, Cheng Yang, Cundong Liu,
https://doi.org/10.18632/aging.203733 pp 25153—25179
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Licochalcone A activation of glycolysis pathway has an anti-aging effect on human adipose stem cells

Yating Wu, Hao Wang, Jianbo Zhu, Haitao Shen, Hailiang Liu,
https://doi.org/10.18632/aging.203734 pp 25180—25194
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YY1 and eIF4A3 are mediators of the cell proliferation, migration and invasion in cholangiocarcinoma promoted by circ-ZNF609 by targeting miR-432-5p to regulate LRRC1

Canghai Guan, Lang Liu, Yuqiao Zhao, Xianhe Zhang, Guanglin Liu, Haicun Wang, Xin Gao, Xiangyu Zhong, Xingming Jiang,
https://doi.org/10.18632/aging.203735 pp 25195—25212
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hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP

Jian Liang, Xing Li, Jian Xu, Guang-Mou Cai, Jian-Xuan Cao, Bo Zhang,
https://doi.org/10.18632/aging.203740 pp 25213—25240
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Endothelial cell–derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway

Shaohua Wang, Min Shi, Jiao Li, Yuanyuan Zhang, Wenjing Wang, Peixin Xu, Yongjun Li,
https://doi.org/10.18632/aging.203742 pp 25241—25255
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MicroRNA therapy confers anti-senescent effects on doxorubicin-related cardiotoxicity by intracellular and paracrine signaling

Wenzheng Xia, Bowen Chang, Liqun Li, Tingting Hu, Jiaqi Ye, Hanbin Chen, Wenfeng Li, Tao Zan, Meng Hou,
https://doi.org/10.18632/aging.203743 pp 25256—25270
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An integrative pan-cancer analysis reveals the oncogenic role of mutS homolog 6 (MSH6) in human tumors

Haibo Zhan, Fengbo Mo, Qiang Xu, Song Wang, Bin Zhang, Xuqiang Liu, Min Dai, Hucheng Liu,
https://doi.org/10.18632/aging.203745 pp 25271—25290
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Sorbitol accumulation decreases oocyte quality in aged mice by altering the intracellular redox balance

Yuexin Zhang, Zhengjie Yan, Hanwen Liu, Lingjun Li, Chun Yuan, Lianju Qin, Lingbo Cai, Jiayin Liu, Yanqiu Hu, Yugui Cui,
https://doi.org/10.18632/aging.203747 pp 25291—25303
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GDI2 is a novel diagnostic and prognostic biomarker in hepatocellular carcinoma

Wen Zhang, Zhongjian Liu, Shilin Xia, Lei Yao, Lan Li, Ziying Gan, Hui Tang, Qiang Guo, Xinmin Yan, Zhiwei Sun,
https://doi.org/10.18632/aging.203748 pp 25304—25324
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Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression

Liming Tian, Dan Ke, Yi Hong, Chong Zhang, Daizhi Tian, Long Chen, Lirui Zhan, Shiqin Zong,
https://doi.org/10.18632/aging.203749 pp 25325—25341
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Protective effects of galangin against H2O2/UVB-induced dermal fibroblast collagen degradation via hsa-microRNA-4535-mediated TGFβ/Smad signaling

Jian-Jr Lee, Shang-Chuan Ng, Yean-Tin Ni, Jian-Sheng Liu, Chih-Jung Chen, Viswanadha Vijaya Padma, Chih-Yang Huang, Wei-Wen Kuo,
https://doi.org/10.18632/aging.203750 pp 25342—25364
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Anemoside B4 sensitizes human colorectal cancer to fluorouracil-based chemotherapy through src-mediated cell apoptosis

Xing He, Jun Tang, He-Zhong Yan, Jiao-Xue Wang, Hai-Qing Li, Xiao-Wei Duan, Sen-Yuan Yu, Xi-Lu Hou, Guo-Bin Liao, Wei Liu,
https://doi.org/10.18632/aging.203751 pp 25365—25376
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Tartary buckwheat flavonoids relieve the tendency of mammary fibrosis induced by HFD during pregnancy and lactation

Xingchi Kan, Juxiong Liu, Xiangyu Cai, Yaping Huang, Ping Xu, Shoupeng Fu, Wenjin Guo, Guiqiu Hu,
https://doi.org/10.18632/aging.203752 pp 25377—25392
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Functional rare variant in a C/EBP beta binding site in NINJ2 gene increases the risk of coronary artery disease

Pengyun Wang, Yifan Wang, Huixin Peng, Jingjing Wang, Qian Zheng, Pengxia Wang, Jing Wang, Hongfu Zhang, Yufeng Huang, Liang Xiong, Rongfeng Zhang, Yunlong Xia, Qing K. Wang, Chengqi Xu,
https://doi.org/10.18632/aging.203755 pp 25393—25407
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lncRNA CASC7 regulates pathological progression of ox-LDL-stimulated atherosclerotic cell models via sponging miR-21 and regulating PI3K/Akt and TLR4/NF-κB signaling pathways

Xueliang Pei, Yongjin Wen, Facai Cui, Zhiyuan Yang, Zhouliang Xie,
https://doi.org/10.18632/aging.203757 pp 25408—25425
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YTHDC1 gene polymorphisms and neuroblastoma susceptibility in Chinese children

Yong Li, Tongyi Lu, Jian Wang, Zhenjian Zhuo, Lei Miao, Zhonghua Yang, Jiao Zhang, Jiwen Cheng, Haixia Zhou, Suhong Li, Li Li, Jing He, Aiwu Li,
https://doi.org/10.18632/aging.203760 pp 25426—25439
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Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function

Dong-Qi Ni, Dan-Dan Ma, Shuang-Li Hao, Wan-Xi Yang, Tamas Kovacs, Fu-Qing Tan,
https://doi.org/10.18632/aging.203763 pp 25440—25452
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A risk model based on autophagy-related lncRNAs for predicting prognosis and efficacy of immunotherapy and chemotherapy in gastric cancer patients

Lei Gao, Juan Xue, Xiaomin Liu, Lei Cao, Ruifang Wang, Liangliang Lei,
https://doi.org/10.18632/aging.203765 pp 25453—25465
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Prognostic value of CDCA3 in kidney renal papillary cell carcinoma

Hao Li, Mi Li, Caihong Yang, Fengjing Guo, Sisi Deng, Lixi Li, Tian Ma, Jiyuan Yan, Hua Wu, Xiaojuan Li,
https://doi.org/10.18632/aging.203767 pp 25466—25483
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Hsa_circ_0008259 modulates miR-21-5p and PDCD4 expression to restrain osteosarcoma progression

Kai Guan, Shizhang Liu, Keke Duan, Xiaoxia Zhang, Huitong Liu, Bingqiang Xu, Xi Wang, Xin Jin,
https://doi.org/10.18632/aging.203769 pp 25484—25495
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A novel 6-gene signature derived from tumor-infiltrating T cells and neutrophils predicts survival of bladder urothelial carcinoma

Xuan Zou, Yong Wei, Tao Qi, Xiaping Wang, Wenren Zuo, Tongshan Wang, Wei Zhu, Xin Zhou,
https://doi.org/10.18632/aging.203770 pp 25496—25517
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Identification of a novel immune signature for optimizing prognosis and treatment prediction in colorectal cancer

Yan Li, Yiyi Li, Zijin Xia, Dun Zhang, Xiaomei Chen, Xinyu Wang, Jing Liao, Wei Yi, Jun Chen,
https://doi.org/10.18632/aging.203771 pp 25518—25549
View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

A novel immune-related long non-coding RNAs risk model for prognosis assessment of lung adenocarcinoma

Songmei Lu, Nan Shan, Xingyue Chen, Fangliang Peng, Yiming Wang, Hao Long,
https://doi.org/10.18632/aging.203772 pp 25550—25563
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CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation

Dabao Yao, Shuo Zhang, Zhengwei Hu, Haiyang Luo, Chengyuan Mao, Yu Fan, Mibo Tang, Fen Liu, Si Shen, Liyuan Fan, Mengjie Li, Jingjing Shi, Jiadi Li, Dongrui Ma, Yuming Xu, Changhe Shi,
https://doi.org/10.18632/aging.203774 pp 25564—25577
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Reviews

G-Quadruplexes and the DNA/RNA helicase DHX36 in health, disease, and aging

Aaron Antcliff, Louise D. McCullough, Andrey S. Tsvetkov,
https://doi.org/10.18632/aging.203738 pp 25578—25587
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Influence of early life stress on depression: from the perspective of neuroendocrine to the participation of gut microbiota

Xi Tan, Longqing Zhang, Danning Wang, Shaodi Guan, Pei Lu, Xiaolin Xu, Hui Xu,
https://doi.org/10.18632/aging.203746 pp 25588—25601
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Correction

Correction for: LncRNA LOC146880 promotes esophageal squamous cell carcinoma progression via miR-328-5p/FSCN1/MAPK axis

Jianwei Tang, Honglei Xu, Qiang Liu, Jianan Zheng, Cheng Pan, Zhihua Li, Wei Wen, Jun Wang, Quan Zhu, Zhibo Wang, Liang Chen,
https://doi.org/10.18632/aging.203705 pp 25602—25603
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