Research Paper Volume 13, Issue 23 pp 25195—25212

YY1 and eIF4A3 are mediators of the cell proliferation, migration and invasion in cholangiocarcinoma promoted by circ-ZNF609 by targeting miR-432-5p to regulate LRRC1


Figure 3. Silencing circ-ZNF609 inhibited cholangiocarcinoma cells migration and invasion. (A) Wound healing assay was used to detect the migration ability of CCA cells after circ-ZNF609 knockdown. (B) The migration and invasive abilities of CCLP-1 and QBC939 were confirmed by transwell assay after silencing circ-ZNF609. (C) Western blot was used to detect EMT-related proteins including E-cadherin, N-cadherin and vimentin. **P< 0.01; ***P< 0.001.