Research Paper Volume 13, Issue 23 pp 25342—25364

Protective effects of galangin against H2O2/UVB-induced dermal fibroblast collagen degradation via hsa-microRNA-4535-mediated TGFβ/Smad signaling

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Figure 10. Effect of galangin on UVB-induced C57BL6/J nude mouse skin photodamage. (A) The schematic procedure of animal experiments. Dorsal skin of four-week-old C57BL6/J nude mice (n = 6) was exposed to UVB radiation and treated with galangin once every two days for 8 weeks (B) Photograph depicting wrinkle formation on the dorsal skin of nude mice due to UVB exposure, followed by topical application of galangin.