Research Paper Volume 13, Issue 23 pp 25496—25517

A novel 6-gene signature derived from tumor-infiltrating T cells and neutrophils predicts survival of bladder urothelial carcinoma


Figure 5. Clinical (AD) and immune (EH) correlation analysis of the identified model in the TCGA-BLCA dataset. (AD) The boxplots showing the change of risk scores among patients with varied clinical characteristics including age (A), TNM stage (B), tumor size (C), and lymph node metastasis (D); horizontal lines: mean, interquartile range (Q25, Q75), and 95% confidence interval. (E-F) Spearman correlation analyses revealed that the estimated risk score was significantly correlated with the immune and stromal constituent proportion in tumor microenvironment. (G, H) The estimated score has significant negative correlation with T cell proportion and positive correlation with neutrophils proportion.