Research Paper Volume 13, Issue 23 pp 25055—25071

IGFBP-6/sonic hedgehog/TLR4 signalling axis drives bone marrow fibrotic transformation in primary myelofibrosis


Figure 1. IGFBP-6 was modulated in PMF patients. (A) z-score expression levels of IGFBP-6 in healthy, JAK2 wild type, and JAK2V617F mutant PMF patients. (B) Correlation analysis between IGFBP-6 and JAK2 expression levels in the PMF patients. (C) mRNA expression of IGFBP-6 in neutrophils of PMF patients. * p<0.05.