Research Paper Volume 13, Issue 24 pp 25763—25777

Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

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Figure 1. Surface markers and functions in stages of T-cell differentiation (in the CD4 and CD8 compartments). −: low expression/not expressed/function not present. +: expressed/function present, and additional +’s: higher expression/function. Abbreviation: SASP: Senescence-associated secretory phenotype.