Editorial Volume 14, Issue 8 pp 3335—3336
SNCA-AS1 in aging and Parkinson’s disease
Figure 1. SNCA-AS1 impact on many cellular processes. Over-expression of SNCA-AS1 in a neural cell line model (SH-SY5Y) leads to a transcriptional dysregulation correlated with numerous processes. These primarily include SNCA and α-syn regulation, dopaminergic, glutamatergic and GABAergic synapses, neurite extension, neural differentiation, cellular senescence, aging, PD and synucleinopathies. The figure is made with Biorender.com.