Research Paper Volume 14, Issue 8 pp 3540—3553

MicroRNA-181a-5p prevents the progression of esophageal squamous cell carcinoma in vivo and in vitro via the MEK1-mediated ERK-MMP signaling pathway


Figure 2. MiR-181a-5p was downregulated in 4 paired human ESCC tissues. (A) H&E staining was used to identified ESCC tissues and their corresponding adjacent peri-cancerous tissue specimens, RT-qPCR of miR-181a-5p expression in human ESCC tissues. *P < 0.05, esophageal squamous cell carcinoma vs. peri-cancerous tissue. (B) Kaplan-Meier's method was used for survival analysis and miR-181 survival curve was drawn. (C) Kaplan-Meier analysis was used to depict the overall survival curves of patients with of ESCC from the data in GSE114110.