Research Paper Volume 14, Issue 8 pp 3569—3596

Effective biomarkers and therapeutic targets of nerve-immunity interaction in the treatment of depression: an integrated investigation of the miRNA-mRNA regulatory networks

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Figure 7. The DEmiRNA-DEG regulatory network in MDD has been identified. Red represents up-regulation, green represents down-regulation, a triangle represents miRNA, and a prototype represents mRNA. There were 23 nodes and 18 interactions in the DEmiR-downDEG regulatory network. There were 23 nodes, with 4 down-regulated DEGs and 3 DEmiRNAs, 13 upregulated DEGs and 3 DEmiRNAs.