Research Paper Volume 14, Issue 8 pp 3569—3596

Effective biomarkers and therapeutic targets of nerve-immunity interaction in the treatment of depression: an integrated investigation of the miRNA-mRNA regulatory networks

class="figure-viewer-img"

Figure 9. DEG enrichment analyses using GO and KEGG. (A) GO functional annotation enriched by DEGs in the GO database; red indicates a low p value and blue indicates a high p value; the size of the bubbles indicates the degree of enrichment, with larger bubbles reflecting a higher gene ratio. A circle plot depicting the top 5 GO functional annotations enriched by DEGs. (B) Pathways significantly enriched by DEGs in the KEGG database; red indicates a low p value and blue indicates a high p value; the size of the bubbles indicates the degree of enrichment, with larger bubbles indicating a higher gene ratio. A circle plot depicting the top 5 KEGG pathways enriched by DEGs.