Figure 8. MELK levels and immune cell infiltration in HCC. (A) Immune cell infiltration in relation to MELK copy number variations. (B) Correlation of MELK levels with B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells. (C) Association between MELK levels (HR = 4.636, 95% CI 1.170, 18.369, p = 0.029) patient OS at 60 months with increased neutrophil. (D) Association between MELK levels and patient OS at 60 months (HR = 6.202, 95% CI 1.578, 24.378, p = 0.009) with increased macrophage.