Research Paper Volume 14, Issue 9 pp 4036—4049

Pentraxin 3 depletion (PTX3 KD) inhibited myocardial fibrosis in heart failure after myocardial infarction


Figure 5. PTX3 KD successfully suppressed the expression of IL-6/STAT3 signals in MI. (A, B) Western blotting was performed to measure the IL-6 and p-STAT as well as fibrosis-associated proteins collagen-I/III expression. Control group vs. PTX3-NC group, *p<0.05, ** p<0.01, *** p<0.001; PTX3-NC group vs. PTX3-KD group, # p<0.05, ## p<0.01, ### p<0.001.