CCL19 has potential to be a potential prognostic biomarker and a modulator of tumor immune microenvironment (TIME) of breast cancer: a comprehensive analysis based on TCGA database

Jinyan Wang; Dongmei Qin; Lingling Ye; Li Wan; Fen Wang; Yan Yang; Yajun Ma; Hui Yang; Zhaohui Yang; Meili Chen; Wen Jiang; Quan&#x2019;an Zhang

doi:doi:10.18632/aging.204081

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Research Paper Volume 14, Issue 9 pp 4158—4175

CCL19 has potential to be a potential prognostic biomarker and a modulator of tumor immune microenvironment (TIME) of breast cancer: a comprehensive analysis based on TCGA database

Figure 4. PPI network construction and univariate COX regression analysis. (A) PPI network was constructed with interaction confidence value >0.95; (B) The top 10 DEGs which shared the leading nodes in PPI network; (C) Univariate COX regression analysis of 223 DEGs. p<0.05 was considered to be statistically significant; (D) Venn plot displayed the DEGs which shared the top 10 leading nodes in PPI network and were significant related with patients’ survival. p<0.05 was considered to be statistically significant.