Research Paper Volume 14, Issue 13 pp 5523—5536

Long non-coding RNA ZNF674-AS1 antagonizes oxaliplatin resistance of gastric cancer via regulating EZH2-mediated methylation of CHST7

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Figure 7. Proposed model for the tumor suppressive role of ZNF674-AS1 in oxaliplatin resistance of GC. ZNF674-AS1 epigenetically silences CHST7 expression via binding to EZH2, which inhibits oxaliplatin resistance of GC.