Research Paper Volume 14, Issue 14 pp 5727—5748

The therapeutic effect of Fufang Zhenshu Tiaozhi (FTZ) on osteoclastogenesis and ovariectomized-induced bone loss: evidence from network pharmacology, molecular docking and experimental validation


Figure 2. Heatmap for top 50 differentially expressed genes (DEGs). (A) Top 50 DEGs of osteoclast differentiation obtained from Robust rank aggregation (RRA) analysis. The color of the cells ranging from yellow to purple represents the logfc value of genes ranging from high to low. (B and C) The dot plot and bar plot show the enrichment results of biological process (B) and KEGG from total osteoclast DEGs based on RRA results (C).