Research Paper Volume 14, Issue 14 pp 5812—5837

Elucidating the pharmacological mechanism by which Si-Wu-Tang induces cellular senescence in breast cancer via multilevel data integration


Figure 6. Prognostic analysis of ASI-related DEGs and establishment of a prognostic model. (A) Forest plot of the univariate Cox analysis of 6 ASI-related DEGs. (B) Correlation network of 6 ASI-related DEGs. (C) LASSO coefficient profiles of 6 ASI-related DEGs. (D) Cross-validation for tuning parameter selection in the LASSO regression. (E) The distribution of risk scores, gene expression levels, and survival status of BRCA patients in the training cohort. (F) Kaplan–Meier curves of the OS of all the BRCA patients in the TCGA cohort based on the risk score. (G) Time-dependent ROC curve analysis of the prognostic model (1, 3, and 5 years).