Research Paper Volume 14, Issue 15 pp 6169—6186

A signature constructed with mitophagy-related genes to predict the prognosis and therapy response for breast cancer


Figure 3. Establishment of a 13-gene signature in TCGA cohort. (A) Differentially expressed genes (DEGs) were penalized by LASSO Cox regression analysis. (B) Cross-validation of candidate genes based on the minimum lambda value. (C) Survival analysis between two risk subgroups. (D) Receiver operating characteristic (ROC) curve of the 13-gene signature. (E) Survival time and status of each breast cancer (BC) sample based on the risk score. (F) Principal component analysis (PCA) of the 13-gene signature.