Research Paper Volume 14, Issue 15 pp 6047—6065

Regulation of microglial activation in stroke in aged mice: a translational study


Figure 2. Cell-membrane inflammatory marker levels in IRF5 or IRF4 CKO vs. flox microglia by flow cytometry performed on stroke and sham brains. (A, C) Representative flow plots of IRF5 CKO, and (E, G) IRF4 CKO microglia gated by CD68 and CD206. (B, D, F, H) Quantification data of MFI for CD68 (B for IRF5, and F for IRF4) and CD206 (D for IRF5, and H for IRF4). n = 4 to 5 per sham and 6 to 7 per stroke group; *P < 0.0500.