Research Paper Volume 14, Issue 17 pp 7126—7136

Zbtb34 promotes embryonic stem cell proliferation by elongating telomere length


Figure 1. Zbtb34 elongates telomere length and increases cell proliferation. The mESCs were transfected with a Zbtb34-EGFP vector or Zbtb34-siRNA. The values of Zbtb34, TERT expression, telomere length, cell proliferation, cell apoptosis and telomerase activity are expressed as fold changes compared with control values normalized to 1. *P < 0.05, **P < 0.01. Abbreviations: mESCs: mouse embryonic stem cells; TERT: telomerase reverse transcriptase.