Research Paper Volume 14, Issue 21 pp 8615—8632

IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons


Figure 2. Histology of representative ovaries from control (PBS) and experimental (RAd-IGF1) 12-months-old MA Sprague Dawley rats. Ovarian sections from non-cycling (above) and cycling rats (below). Abbreviations: CL: corpora lutea; FA: atretic follicles; FO: ovarian follicles; OC: ovarian cysts. Total magnification of 100× (scale bar: 200 microns).