Research Paper Volume 14, Issue 21 pp 8805—8817

Desmocollin-2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma via the ERK/c-MYC signaling pathway

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Figure 4. DSC2 inhibits HCC tumor growth in vivo. (A) LM3 cells transfected with vector and overExp-DSC2 were injected into the right back of 5-week-old male nude mice with 6 rats in each group. After 28 days, the tumor was collected, and the volume and weight of the tumor were measured. (B) 7721 cells transfected with shControl and shRNA-DSC2-1 were injected into the right back of 5-week-old male nude mice with 6 rats in each group. After 28 days, the tumor was collected, and the volume and weight of the tumor were measured.