Research Paper Volume 14, Issue 22 pp 9020—9036

Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer


Figure 1. Landscape of pyroptosis related genes in colon cancer. (A) The protein-protein interactions (PPI) network between pyroptosis genes using STRING database. (B) GO functional enrichment analyses for pyroptosis-related genes. (C) The mutation landscape of pyroptosis genes in TCGA-COAD cohort. (D) The mutation co-occurrence and exclusion analyses for these genes. (E) The copy number variation frequency of pyroptosis genes. (F) Expression of pyroptosis genes in tumor and normal samples based on TCGA-COAD cohort. (G) Survival analyses for the pyroptosis genes using univariate Cox regression model.